Tapering of biological treatment in autoinflammatory diseases: a scoping review.

ABSTRACT:

Background

Biological treatment and treat-to-target approaches guide the achievement of inactive disease and clinical remission in Autoinflammatory Diseases (AID). However, there is limited evidence addressing optimal tapering strategies and/or discontinuation of biological treatment in AID. This study evaluates available evidence of tapering biological treatment and explores key factors for successful tapering.

Methods

A systematic literature search was conducted in Embase, MEDLINE, Cochrane Database of Systematic Reviews and Cochrane Central Register of Controlled Trials using the OVID platform (1990-08/2020). Bibliographic search of relevant reviews was also performed. Studies/case series (n ≥ 5) in AID patients aged ≤ 18 years with biological treatment providing informat

SUBMITTER: Welzel T 

PROVIDER: S-EPMC9375310 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature