Logic of the Temporal Compartmentalization of the Hepatic Metabolic Cycle.
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ABSTRACT:
SUBMITTER: Zhu B
PROVIDER: S-EPMC9394779 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
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Logic of the Temporal Compartmentalization of the Hepatic Metabolic Cycle.
Physiology (Bethesda, Md.) 20220606 5
The mammalian liver must cope with various metabolic and physiological changes that normally recur every day and result primarily from rest-activity and fasting-feeding cycles. In this article, I present evidence supporting a temporal compartmentalization of rhythmic hepatic metabolic processes into four main clusters: regulation of energy homeostasis, maintenance of information integrity, immune response, and genetic information flow. I further review literatures and discuss how both the circad ...[more]
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