Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC9404705 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Wang Yang Y Xia Wenying W Shen Fangrong F Zhou Jinhua J Gu Yanzheng Y Chen Youguo Y
Oncology letters 20220809 4
A transfer RNA (tRNA)-derived fragment (tRF) was found to be a new possible biological marker and target in carcinoma therapy. However, the effect exerted by tRFs on cervical carcinoma remains unclear. In the present study, the potential tumor suppressor gene tRF-Glu49 was identified in cervical carcinoma through tRF and tiRNA microarray investigation. A reverse transcription-quantitative PCR assay then demonstrated that tRF-Glu49 was downregulated in the cervical carcinoma tissue. Further clini ...[more]