A Portable 'Plug-and-Play' Fibre Optic Sensor for In-Situ Measurements of pH Values for Microfluidic Applications.

ABSTRACT: Microfluidics is used in many applications ranging from chemistry, medicine, biology and biomedical research, and the ability to measure pH values in-situ is an important parameter for creating and monitoring environments within a microfluidic chip for many such applications. We present a portable, optical fibre-based sensor for monitoring the pH based on the fluorescent intensity change of an acrylamidofluorescein dye, immobilized on the tip of a multimode optical fibre, and its performance is evaluated in-situ in a microfluidic channel. The sensor showed a sigmoid response over the pH range of 6.0-8.5, with a maximum sensitivity of 0.2/pH in the mid-range at pH 7.5. Following its evaluation, the sensor developed was used in a single microfluidic PDMS channel and its response was monitore

SUBMITTER: Kumar R 

PROVIDER: S-EPMC9416338 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature