A comprehensive overview on Micro RNA signature in type 2 diabetes Mellitus and its complications.

ABSTRACT: MicroRNAs (miRNAs) are small endogenous, non-coding RNA molecules that can modulate the expression of their target genes. Since its discovery, an enormous breakthrough has been established regarding its biogenesis and pathophysiological action, which has revolutionized the field of molecular biology. In addition, recent studies have identified the existence of stable extracellular/circulating miRNAs tissues and in biological fluids like blood where they are safeguarded from endogenous ribonuclease activity. Type 2 diabetes mellitus (T2DM) has emerged as a prime health issue worldwide. Incidence has increased considerably over the past decade. There are various tests that have been employed to diagnose T2DM. But for early detection and development, the establishment of biomarkers are of par

SUBMITTER: Mishra S 

PROVIDER: S-EPMC9441834 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature