A tale of two connectivities: intra- and inter-subject functional connectivity jointly enable better prediction of social abilities.

ABSTRACT: Naturalistic functional magnetic resonance imaging (fMRI) paradigms, such as movie viewing, are attracting increased attention, given their ability to mimic the real-world cognitive demands on attention and multimodal sensory integration. Moreover, naturalistic paradigms allow for characterizing brain network responses associated with dynamic social cognition in a model-free manner using inter-subject functional connectivity (ISFC). While intra-subject functional connectivity (FC) characterizes the individual's brain functional architecture, ISFC characterizes the neural coupling driven by time-locked extrinsic dynamic stimuli across individuals. Here, we hypothesized that ISFC and FC provide distinct and complementary information about individual differences in social cognit

SUBMITTER: Xie H 

PROVIDER: S-EPMC9475068 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature