Cardiovascular disease and risk of lung cancer incidence and mortality: A nationwide matched cohort study.

ABSTRACT:

Purpose

Previous studies have suggested a link between cardiovascular disease (CVD) and the subsequent development of lung cancer. However, empirical evidence on the association of CVDs, particularly type-specific CVDs, with lung cancer incidence and survival remains limited.

Methods

The cohort study included 306,285 patients with CVD and 1,222,140 individuals without CVD. We performed stratified Cox regression to estimate the hazard ratio (HR).

Results

During up to 42 years of follow-up, 243 (0.08%) and 537 (0.04%) participants were diagnosed with lung cancer among CVD patients and matched individuals, respectively. Patients with CVD had a 67% increased risk of lung cancer (HR: 1.67, 95% confidence interval [CI]: 1.42-1.96). The increased risks were observed in patie

SUBMITTER: Wang C 

PROVIDER: S-EPMC9486704 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature