Domestic cat hepadnavirus associated with hepatopathy in cats: A retrospective study.

ABSTRACT:

Background

Whether domestic cat hepadnavirus (DCH) infection is associated with clinical disease remains to be determined.

Objectives

To determine the relationship between DCH detection, hematology, serum bichemistry and liver histology in DCH-positive cats.

Animals

One thousand twenty-two cats in Thailand without concurrent diseases and not undergoing treatments adversely affecting the liver.

Methods

Retrospective cross-sectional study. Samples derived from cats with concurrent virus detection were excluded. DCH detection was determined in blood and fresh-frozen liver by quantitative polymerase chain reaction (qPCR) and further investigated in liver sections showing histological parenchymal disorders (HPD) and normal liver (HNL) using in situ hybridization (IS

SUBMITTER: Piewbang C 

PROVIDER: S-EPMC9511090 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature