Cardiorespiratory fitness, white blood cell count, and mortality in men and women.

ABSTRACT:

Background

We examined the associations of cardiorespiratory fitness (CRF) and white blood cell count (WBC) with mortality outcomes.

Methods

A total of 52,056 apparently healthy adults completed a comprehensive health examination, including a maximal treadmill test and blood chemistry analyses. CRF was categorized as high, moderate, or low by age and sex; WBC was categorized as sex-specific quartiles.

Results

During 17.8 ± 9.5 years (mean ± SD) of follow-up, a total of 4088 deaths occurred. When regressed jointly, significantly decreased all-cause mortality across CRF categories was observed within each quartile of WBC in men. Within WBC Quartile 1, all-cause mortality hazard ratios (HRs) with a 95% confidence interval (95%CI) were 1.0 (referent), 1.29 (95%CI: 1.06‒1.

SUBMITTER: Farrell SW 

PROVIDER: S-EPMC9532609 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature