Correlation of dehydroepiandrosterone with diabetic nephropathy and its clinical value in early detection.

ABSTRACT:

Aims/introduction

This study was carried out to assess the association of dehydroepiandrosterone (DHEA) with diabetic nephropathy (DN) in patients with type 2 diabetes mellitus to better predict the progression of diabetic nephropathy.

Materials and methods

A total of 1,082 patients with type 2 diabetes mellitus in the Department of Endocrinology and Metabolism of Tianjin Medical University General Hospital were enrolled in this study, and grouped for comparison. The effect of serum DHEA on DN was evaluated by multivariate logistic regression analysis, and receiver operating characteristic curves were established to explore the optimal concentration of DHEA in patients with DN and non-DN.

Results

DHEA was significantly decreased in patients with DN (P < 0.001). The pr

SUBMITTER: Ma Y 

PROVIDER: S-EPMC9533038 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature