Fibromyalgia in women: association of inflammatory plasma proteins, muscle blood flow, and metabolism with body mass index and pain characteristics.

ABSTRACT:

Introduction

Obesity is a common comorbidity in fibromyalgia (FM). Both FM and obesity have been connected to low-grade inflammation, although it is possible that previously reported inflammatory alterations in FM primarily may be linked to increased body mass index (BMI).

Objective

This study aimed to investigate whether the inflammatory plasma protein profile, muscle blood flow, and metabolism and pain characteristics (clinical parameters and patient-reported outcome measurements) differed between female patients with FM with and without obesity.

Methods

Patients with FM underwent clinical examinations, physical tests, and answered questionnaires. They were dichotomized according to BMI (<30 kg/m² [n = 14]; ≥30 kg/m² [n = 13]). Blood samples we

SUBMITTER: Ghafouri B 

PROVIDER: S-EPMC9534367 | biostudies-literature | 2022 Nov-Dec

REPOSITORIES: biostudies-literature