Directional and inter-acquisition variability in diffusion-weighted imaging and editing for restricted diffusion.

ABSTRACT:

Purpose

To evaluate and quantify inter-directional and inter-acquisition variation in diffusion-weighted imaging (DWI) and emphasize signals that report restricted diffusion to enhance cancer conspicuity, while reducing the effects of local microscopic motion and magnetic field fluctuations.

Methods

Ten patients with biopsy-proven prostate cancer were studied under an Institutional Review Board-approved protocol. Individual acquisitions of DWI signal intensities were reconstructed to calculate inter-acquisition distributions and their statistics, which were compared for healthy versus cancer tissue. A method was proposed to detect and filter the acquisitions affected by motion-induced signal loss. First, signals that reflect restricted diffusion were separated from the acqui

SUBMITTER: Gundogdu B 

PROVIDER: S-EPMC9545544 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature