Evaluation of psychometric properties of patient-reported outcome measures frequently used in narcolepsy randomized controlled trials: a systematic review.

ABSTRACT:

Study objectives

To systematically determine subjective and objective outcome measures used to measure the efficacy of narcolepsy interventions in randomized controlled trials (RCTs) in adults and children and assess psychometric properties of patient-reported outcome measures (PROMs) used.

Methods

We searched bibliographical databases and clinical trial registries for narcolepsy RCTs and extracted objective and subjective outcome measures. If PROMs were used, we searched for psychometric studies conducted in a narcolepsy population using bibliographical databases and appraised using Consensus-based Standards for the Selection of Health Measurement Instruments (COSMIN) guidelines.

Results

In total, 80 different outcome measures were used across 100 RCTs. Epworth Sleep

SUBMITTER: Schokman A 

PROVIDER: S-EPMC9548672 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature