The association of serum vitamin D with incident diabetes in an African American population.

ABSTRACT:

Background

Incident diabetes risk is inversely proportional to 25-hydroxyvitamin D [25(OH)D] levels among non-Hispanic white but is unclear among African American (AA) populations. Serum 25(OH)D2 may be an important component of total 25(OH)D among AA populations due to higher levels of melanin.

Objective

To assess the association of serum 25(OH)D with incident diabetes among AAs and stratify by detectable 25(OH)D2.

Design

Serum 25(OH)D2 and 25(OH)D3 were collected from 2000 to 2004 among AA participants in the Jackson Heart Study. A cosinor model was used to adjust for the seasonality of 25(OH)D3; 25(OH)D3 and 25(OH)D2 were combined to ascertain total 25(OH)D. Incident diabetes (fasting glucose ≥126 mg/dl, use of diabetes drugs, or HbA1c ≥6.5%) was assessed over 12 y

SUBMITTER: Joseph JJ 

PROVIDER: S-EPMC9562299 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature