Study on the vasodilatory activity of lotus leaf extract and its representative substance nuciferine on thoracic aorta in rats.
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ABSTRACT:
SUBMITTER: Deng H
PROVIDER: S-EPMC9581309 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
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Study on the vasodilatory activity of lotus leaf extract and its representative substance nuciferine on thoracic aorta in rats.
Deng Hao H Xu Qian Q Sang Xiao-Tong XT Huang Xing X Jin Li-Li LL Chen Fen-Er FE Shen Qing-Kun QK Quan Zhe-Shan ZS Cao Li-Hua LH
Frontiers in pharmacology 20221005
Lotus (<i>Nelumbo nucifera</i>) leaves are widely used for both edible and medicinal applications. For its further utilization, we studied the vasodilatory activity of lotus leaf extract for the first time. In this study, we obtained the extracts using different ratios of water and ethanol, which was followed by polarity-dependent extraction. We found that the CH<sub>2</sub>Cl<sub>2</sub> layer exhibited better vasodilatory activity (EC<sub>50</sub> = 1.21 ± 0.10 μg/ml). HPLC and ESI-HRMS analys ...[more]
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