Early brain and abdominal oxygenation in extremely low birth weight infants.

ABSTRACT:

Background

Extremely low birth weight (ELBW) infants are at risk for end-organ hypoxia and ischemia. Regional tissue oxygenation of the brain and gut as monitored with near-infrared spectroscopy (NIRS) may change with postnatal age, but normal ranges are not well defined.

Methods

A prospective study of ELBW preterm infants utilized NIRS monitoring to assess changes in cerebral and mesenteric saturation (Csat and Msat) over the first week after birth. This secondary study of a multicenter trial comparing hemoglobin transfusion thresholds assessed cerebral and mesenteric fractional tissue oxygen extraction (cFTOE and mFTOE) and relationships with perinatal variables.

Results

In 124 infants, both Csat and Msat declined over the first week, with a corresponding increase i

SUBMITTER: Chock VY 

PROVIDER: S-EPMC9588487 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature