Endometrial gene expression differences in women with coronavirus disease 2019.

ABSTRACT:

Objective

To study the potential effect of coronavirus disease (COVID-19) on the endometrial transcriptome of affected, symptomatic women for the detection of altered gene expression.

Design

Pilot study of the endometrial transcriptomes of women manifesting COVID-19 compared with those of women without COVID-19 undergoing hysteroscopic procedures for benign gynecologic disorders using RNA sequencing.

Setting

Hospital and university laboratories.

Patient(s)

Women with (n = 14) and without a COVID-19 (n = 10) diagnosis based on a nasopharyngeal swab analysis using quantitative reverse-transcription polymerase chain reaction. The endometrium of the patients with COVID-19 had previously been tested for severe acute respiratory syndrome coronavirus 2 infection, reve

SUBMITTER: de Miguel-Gomez L 

PROVIDER: S-EPMC9624514 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature