Protection against Omicron from Vaccination and Previous Infection in a Prison System.

ABSTRACT:

Background

Information regarding the protection conferred by vaccination and previous infection against infection with the B.1.1.529 (omicron) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is limited.

Methods

We evaluated the protection conferred by mRNA vaccines and previous infection against infection with the omicron variant in two high-risk populations: residents and staff in the California state prison system. We used a retrospective cohort design to analyze the risk of infection during the omicron wave using data collected from December 24, 2021, through April 14, 2022. Weighted Cox models were used to compare the effectiveness (measured as 1 minus the hazard ratio) of vaccination and previous infection across combinations of vaccination histo

SUBMITTER: Chin ET 

PROVIDER: S-EPMC9634863 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature