Reduction of intrafraction pancreas motion using an abdominal corset compatible with proton therapy and MRI.

ABSTRACT:

Background and purpose

Motion mitigation is of crucial importance in particle therapy (PT) of patients with abdominal tumors to ensure high-precision irradiation. Magnetic resonance imaging (MRI) is an excellent modality for target volume delineation and motion estimation of mobile soft-tissue tumors. Thus, the aims of this study were to develop an MRI- and PT-compatible abdominal compression device, to investigate its effect on pancreas motion reduction, and to evaluate patient tolerability and acceptance.

Materials and methods

In a prospective clinical study, 16 patients with abdominal tumors received an individualized polyethylene-based abdominal corset. Pancreas motion was analyzed using time- and phase resolved MRI scans (orthogonal 2D-cine and 4D MRI) with and without

SUBMITTER: Schneider S 

PROVIDER: S-EPMC9672128 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature