Combination of Se-methylselenocysteine, D-α-tocopheryl succinate, β-carotene, and L-lysine can prevent cancer metastases using as an adjuvant therapy.

ABSTRACT:

Objectives

Primary tumor treatment through surgical resection and adjuvant therapy has been extensively studied, but there is a lack of effective strategies and drugs for the treatment of tumor metastases. Here, we describe a functional product based on a combination of compounds, which can be used as an adjuvant therapy and has well-known mechanisms for inhibiting cancer metastases, improving anti-cancer treatment, and enhancing immunity and antioxidant capacity. Our designed combination, named MVBL, consists of four inexpensive compounds: L-selenium-methylselenocysteine (MSC), D-‍α‍-tocopheryl succinic acid (VES), β‍-carotene (β‍-Ca), and L-lysine (Lys).

Methods

The effects of MVBL on cell viability, cell cycle, cell apoptosis, cell migration, cell invasion, reactive oxyge

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC9676092 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature