Detection of Antibiotic Resistance Genes in Pseudomonas aeruginosa by Whole Genome Sequencing.

ABSTRACT:

Background

Multidrug-resistant Pseudomonas aeruginosa has become a hazard to public health, making medical treatment challenging and ineffective. Whole-genome sequencing for antibiotic susceptibility testing offers a powerful replacement for conventional microbiological methods.

Objective

The present study evaluated the presence of antibiotic resistance genes in selected clinical strains of P. aeruginosa using whole-genome sequencing for antibiotic susceptibility testing.

Results

Whole-genome sequencing of P. aeruginosa susceptible to common antibiotics showed the presence of 4 antibiotic resistance gene types, fosA, catB7, blaPAO, and blaOXA-50. Whole genome sequencing of resistant or multidrug-resistant P. aeruginosa showed the presence o

SUBMITTER: Ahmed OB 

PROVIDER: S-EPMC9680685 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature