Endothelial Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.

ABSTRACT:

Objectives

To review, analyze, and synthesize the literature on endothelial dysfunction in critically ill children with multiple organ dysfunction syndrome and to develop a consensus biomarker-based definition and diagnostic criteria.

Data sources

Electronic searches of PubMed and Embase were conducted from January 1992 to January 2020, using a combination of medical subject heading terms and key words to define concepts of endothelial dysfunction, pediatric critical illness, and outcomes.

Study selection

Studies were included if they evaluated critically ill children with endothelial dysfunction, evaluated performance characteristics of assessment/scoring tools to screen for endothelial dysfunction, and assessed outcomes related to mortality, functional status, organ

SUBMITTER: Pierce RW 

PROVIDER: S-EPMC9754809 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature