Effects of non-invasive brain stimulation in dystonia: a systematic review and meta-analysis.

ABSTRACT:

Background

Deep brain stimulation is a highly effective treatment of dystonia but is invasive and associated with risks, such as intraoperative bleeding and infections. Previous research has used non-invasive brain stimulation (NIBS) in an attempt to alleviate symptoms of dystonia. The results of these studies, however, have been variable, leaving efficacy unclear.

Objectives

This study aimed to evaluate the effects of NIBS on symptoms of dystonia and determine whether methodological characteristics are associated with variability in effect size.

Methods

Web of Science, Embase, and MEDLINE Complete databases were searched for articles using any type of NIBS as an intervention in dystonia patients, with changes in dystonia symptoms the primary outcome of interest.

R

SUBMITTER: Morrison-Ham J 

PROVIDER: S-EPMC9793065 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature