Retrograde dye perfusion of the proximal aorta - A postmortem technical study.

ABSTRACT:

Introduction

Multiple cardiovascular conditions can lead to unexpected fatality, which is defined as sudden cardiac death. One of these potentially underlying conditions is aortic regurgitation, which can be caused by discrete changes of the geometry of the proximal aorta. To analyze aortic valve competency and furthermore to elucidate underlying pathological alterations of the coronary arteries and the vasa vasorum a perfusion method to simulate a diastolic state was designed.

Material and methods

A postmortem approach with retrograde perfusion of the ascending aorta with methylene blue was applied to three bodies. The procedure comprised cannulation of the brachiocephalic trunk, clamping of the aortic arch between brachiocephalic trunk and left carotid artery, infusion of

SUBMITTER: Federspiel JM 

PROVIDER: S-EPMC9830167 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature