Transient oscillation dynamics during sleep provide a robust basis for electroencephalographic phenotyping and biomarker identification.

ABSTRACT: Transient oscillatory events in the sleep electroencephalogram represent short-term coordinated network activity. Of particular importance, sleep spindles are transient oscillatory events associated with memory consolidation, which are altered in aging and in several psychiatric and neurodegenerative disorders. Spindle identification, however, currently contains implicit assumptions derived from what waveforms were historically easiest to discern by eye, and has recently been shown to select only a high-amplitude subset of transient events. Moreover, spindle activity is typically averaged across a sleep stage, collapsing continuous dynamics into discrete states. What information can be gained by expanding our view of transient oscillatory events and their dynamics? In this paper, we develo

SUBMITTER: Stokes PA 

PROVIDER: S-EPMC9832519 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature