No difference in outcomes between large- and small-pore meshes in a prospective, randomized, multicenter trial investigating open retromuscular meshplasty for incisional hernia repair.

ABSTRACT:

Study design

A randomized, controlled, prospective multicenter clinical trial with a parallel group design was initiated in eight surgical centers to compare a large-pore polypropylene mesh (Ultrapro^®) to a small-pore polypropylene mesh (Premilene^®) within a standardized retromuscular meshplasty for incisional hernia repair.

Methods

Between 2004 and 2006, patients with a fascial defect with a minimum diameter of 4 cm after vertical midline laparotomy were recruited for the trial. Patients underwent retromuscular meshplasty with either a large-pore or a small-pore mesh to identify the superiority of the large-pore mesh. Follow-up visits were scheduled at 5 and 21 days and 4, 12, and 24 months after surgery. A clinical examination, a modified short form 3

SUBMITTER: Kroh A 

PROVIDER: S-EPMC9836964 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature