Mining novel cis-regulatory elements from the emergent host Rhodosporidium toruloides using transcriptomic data.

ABSTRACT: The demand for robust microbial cell factories that produce valuable biomaterials while resisting stresses imposed by current bioprocesses is rapidly growing. Rhodosporidium toruloides is an emerging host that presents desirable features for bioproduction, since it can grow in a wide range of substrates and tolerate a variety of toxic compounds. To explore R. toruloides suitability for application as a cell factory in biorefineries, we sought to understand the transcriptional responses of this yeast when growing under experimental settings that simulated those used in biofuels-related industries. Thus, we performed RNA sequencing of the oleaginous, carotenogenic yeast in different contexts. The first ones were stress-related: two conditions of high temperature (37 and 42°C) a

SUBMITTER: Nora LC 

PROVIDER: S-EPMC9853887 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature