Mixotrophic chain elongation with syngas and lactate as electron donors.

ABSTRACT: Feeding microbial communities with both organic and inorganic substrates can improve sustainability and feasibility of chain elongation processes. Sustainably produced H₂ , CO₂ , and CO can be co-fed to microorganisms as a source for acetyl-CoA, while a small amount of an ATP-generating organic substrate helps overcome the kinetic hindrances associated with autotrophic carboxylate production. Here, we operated two semi-continuous bioreactor systems with continuous recirculation of H₂ , CO₂ , and CO while co-feeding an organic model feedstock (lactate and acetate) to understand how a mixotrophic community is shaped during carboxylate production. Contrary to the assumption that H₂ , CO₂ , and CO support chain elongation via et

SUBMITTER: Baleeiro FCF 

PROVIDER: S-EPMC9871530 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature