Gut microbiota and microbiota-derived metabolites promotes endometriosis.

ABSTRACT: Endometriosis is a pathological condition of the female reproductive tract characterized by the existence of endometrium-like tissue at ectopic sites, affecting 10% of women between the age 15 and 49 in the USA. However, currently there is no reliable non-invasive method to detect the presence of endometriosis without surgery and many women find hormonal therapy and surgery as ineffective in avoiding the recurrences. There is a lack of knowledge on the etiology and the factors that contribute to the development of endometriosis. A growing body of recent evidence suggests an association between gut microbiota and endometriosis pathophysiology. However, the direct impact of microbiota and microbiota-derived metabolites on the endometriosis disease progression is largely unknown. To understan

SUBMITTER: Chadchan SB 

PROVIDER: S-EPMC9873805 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature