Investigating associations of omega-3 fatty acids, lung function decline, and airway obstruction.

ABSTRACT:

Rationale

Inflammation contributes to lung function decline and the development of chronic obstructive pulmonary disease. Omega-3 fatty acids have anti-inflammatory properties and may benefit lung health.

Objectives

Investigate associations of omega-3 fatty acids with lung function decline and incident airway obstruction in adults of diverse races/ethnicities from general population cohorts.

Methods

Complementary study designs: (1) longitudinal study of plasma phospholipid omega-3 fatty acids and repeated FEV ₁ and FVC measures in the National Heart, Lung, and Blood Institute Pooled Cohorts Study, and (2) two-sample Mendelian Randomization (MR) study of genetically predicted omega-3 fatty acids and lung function parameters.

Measurements and main results<

SUBMITTER: Patchen BK 

PROVIDER: S-EPMC9882557 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature