Brain diffusion alterations in patients with COVID-19 pathology and neurological manifestations.

ABSTRACT:

Background and objective

COVID-19 neurological manifestations have been progressively recognized. Among available MRI techniques, diffusion weighted imaging (DWI) shows promise to study microstructure, inflammation, and edema. Previous DWI studies reported alterations in brain diffusivity in COVID-19 patients, as assessed by morphologic evaluation of brain DWI scans only. The aim of this study was to assess and quantify brain diffusion alterations in COVID-19 patients with neurological manifestations.

Methods

215 COVID-19 patients with neurological manifestations (olfactory and/or other neurological disorders) and 36 normal controls were compared and studied with DWI and T1-weighted MRI scans. MRI scans were processed by a semi-automatic processing procedure specifically dev

SUBMITTER: Caroli A 

PROVIDER: S-EPMC9883079 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature