High physical activity alleviates the adverse effect of higher sedentary time on the incidence of chronic kidney disease.

ABSTRACT:

Background

Low physical activity (PA) increases the prevalence of chronic kidney disease (CKD). This study aimed to investigate the effects of PA and sedentary time (ST) on the changes in renal function and the development of CKD in the middle-aged Korean population.

Methods

From the Korean Genome and Epidemiology Study Database, 7988 participants in their 40s and 60s were identified and stratified by (1) PA: high-PA (>24 MET-h/day), moderate-PA (9-24 MET-h/day) and low-PA (<9 MET-h/day); and (2) ST: high-ST (>6 h/day), moderate-ST (3-6 h/day) and low-ST (<3 h/day). Incident CKD was defined as estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m² following the Chronic Kidney Disease Epidemiology Collaboration equation.

Results

The mean age of the

SUBMITTER: Oh W 

PROVIDER: S-EPMC9891972 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature