Sedentary time and postmenopausal breast cancer incidence.

ABSTRACT:

Purpose

The objective of this study was to evaluate the prospective association between sedentary time and postmenopausal breast cancer incidence, and whether associations differ by race/ethnicity, physical activity levels, and body measurements.

Methods

The Women's Health Initiative Observational Study is a prospective cohort among women ages 50-79 years at baseline (1994-1998) (analytic cohort = 70,233). Baseline questionnaire data were used to estimate time spent sitting and total sedentary time. Associations between time spent sitting and invasive breast cancer incidence overall (n = 4,115 cases through September 2015), and by hormone receptor subtypes, were investigated using Cox proportional hazards regression. Analyses were replicated stratified by race/ethnicity, bod

SUBMITTER: Nomura SJO 

PROVIDER: S-EPMC5687985 | biostudies-literature | 2017 Dec

REPOSITORIES: biostudies-literature