Choriocapillaris Flow Signal Impairment in Patients With Pseudoxanthoma Elasticum.

ABSTRACT:

Purpose

To quantify choriocapillaris flow alterations in patients with pseudoxanthoma elasticum (PXE) in pre-atrophic stages and its association with structural changes of the choroid and outer retina.

Methods

Thirty-two eyes of 21 patients with PXE and 35 healthy eyes of 35 controls were included. The density of choriocapillaris flow signal deficits (FDs) was quantified on 6 × 6-mm optical coherence tomography angiography (OCTA) images. Spectral-domain optical coherence tomography (SD-OCT) images were analyzed for thicknesses of the choroid and outer retinal microstructure and correlated with choriocapillaris FDs in the respective Early Treatment Diabetic Retinopathy Study subfield.

Results

The multivariable mixed model analysis for choriocapillaris FDs revealed sign

SUBMITTER: Loewinger AS 

PROVIDER: S-EPMC9946047 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature