Ventilatory ratio and mechanical power in prolonged mechanically ventilated COVID-19 patients versus respiratory failures of other etiologies.

ABSTRACT:

Background

Evidence suggests differences in ventilation efficiency and respiratory mechanics between early COVID-19 pneumonia and classical acute respiratory distress syndrome (ARDS), as measured by established ventilatory indexes, such as the ventilatory ratio (VR; a surrogate of the pulmonary dead-space fraction) or mechanical power (MP; affected, e.g., by changes in lung-thorax compliance).

Objectives

The aim of this study was to evaluate VR and MP in the late stages of the disease when patients are ready to be liberated from the ventilator after recovering from COVID-19 pneumonia compared to respiratory failures of other etiologies.

Design

A retrospective observational cohort study of 249 prolonged mechanically ventilated, tracheotomized patients with and without

SUBMITTER: Ghiani A 

PROVIDER: S-EPMC9971705 | biostudies-literature | 2023 Jan-Dec

REPOSITORIES: biostudies-literature