Enrollment of Participants From Marginalized Racial and Ethnic Groups: A Comparative Assessment of the STEADY-PD III and SURE-PD3 Trials.

ABSTRACT:

Background and objectives

Representation of persons from marginalized racial and ethnic groups in Parkinson disease (PD) trials has been low, limiting the generalizability of therapeutic options for individuals with PD. Two large phase 3 randomized clinical trials sponsored by the National Institute of Neurological Disorders and Stroke (NINDS), STEADY-PD III and SURE-PD3, screened participants from overlapping Parkinson Study Group clinical sites under similar eligibility criteria but differed in participation by underrepresented minorities. The goal of this research is to compare recruitment strategies of PD participants belonging to marginalized racial and ethnic groups.

Methods

A total of 998 participants with identified race and ethnicity consented to STEADY-PD III and S

SUBMITTER: Di Luca DG 

PROVIDER: S-EPMC9973288 | biostudies-literature | 2023 Feb

REPOSITORIES: biostudies-literature