Risk factors for structural and functional progression of primary open-angle glaucoma in an African ancestry cohort.

ABSTRACT:

Background/aims

To investigate the rates of structural and functional progression of primary open-angle glaucoma in an African ancestry cohort and identify risk factors for progression.

Methods

This retrospective study included 1424 eyes from glaucoma cases in the Primary Open-Angle African American Glaucoma Genetics cohort, with ≥2 visits for retinal nerve fibre layer (RNFL) thickness and mean deviation (MD) measurements over ≥6-month follow-up. The rates of structural progression (change in RNFL thickness/year) and functional progression (change in MD/year) were calculated from linear mixed effects models, accounting for intereye correlation and longitudinal correlation. Eyes were categorised as slow, moderate or fast progressors. Risk factors for progression rates were as

SUBMITTER: Salowe RJ 

PROVIDER: S-EPMC9990679 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature