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Smallbone2013 - Human metabolism global reconstruction (recon 2.1x)


ABSTRACT:

Smallbone2013 - Human metabolism global reconstruction (recon 2.1x)

Recon 2.1x.

This model is described in the article:

Kieran Smallbone
Molecular Networks (q-bio.MN)

Abstract:

Recon 2 is a highly curated reconstruction of the human metabolic network. Whilst the network is state of the art, it has shortcomings, including the presence of unbalanced reactions involving generic metabolites. By replacing these generic molecules with each of their specific instances, we can ensure full elemental balancing, in turn allowing constraint-based analyses to be performed. The resultant model, called Recon 2.1, is an order of magnitude larger than the original.

To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to CC0 Public Domain Dedication for more information.

SUBMITTER: Kieran Smallbone 

PROVIDER: MODEL1311110001 | biostudies-other |

SECONDARY ACCESSION(S): 10.48550/arXiv.1311.5696

REPOSITORIES: biostudies-other

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Publications

Identification of the full-length coding sequence for human galactosyltransferase (beta-N-acetylglucosaminide: beta 1,4-galactosyltransferase).

Masri K A KA   Appert H E HE   Fukuda M N MN  

Biochemical and biophysical research communications 19881201 2


A lambda gt11 human placenta cDNA library was screened using a cDNA probe encoding the COOH-terminal region of human beta 1,4-galactosyltransferase and with a synthetic oligonucleotide having a sequence corresponding to that of the 5' end of the cDNA probe. The newly isolated cDNA was found to code for the NH2-terminal and the 5'-untranslated region, primed at an (A)8 region in the coding sequence. A complete amino acid sequence has been deduced which shows only one membrane anchoring domain nea  ...[more]

Publication: 1/2787

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