Dataset Information
Rozendaal2018 - Model Integrating Glucose and Lipid Dynamics
Ontology highlight
ABSTRACT:
SUBMITTER: Rozendaal YJW
PROVIDER: MODEL1803200001 | biostudies-other |
SECONDARY ACCESSION(S): 29879115
REPOSITORIES: biostudies-other
Publications
In vivo and in silico dynamics of the development of Metabolic Syndrome.
PLoS computational biology 20180607 6
The Metabolic Syndrome (MetS) is a complex, multifactorial disorder that develops slowly over time presenting itself with large differences among MetS patients. We applied a systems biology approach to describe and predict the onset and progressive development of MetS, in a study that combined in vivo and in silico models. A new data-driven, physiological model (MINGLeD: Model INtegrating Glucose and Lipid Dynamics) was developed, describing glucose, lipid and cholesterol metabolism. Since class ...[more]
