Dataset Information
Sips2015 - Glucose and non-esterified fatty acids (NEFA) metabolism
Ontology highlight
ABSTRACT: This a model from the article:
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State.
Fianne L. P. Sips, Elin Nyman, Martin Adiels, Peter A. J. Hilbers, Peter Strålfors, Natal A. W. van Riel, Gunnar Cedersund.PLoS ONE 10(9): e0135665. link,
SUBMITTER: Fianne Sips
PROVIDER: MODEL1806080001 | biostudies-other |
SECONDARY ACCESSION(S): 26356502
REPOSITORIES: biostudies-other
Publications
Model-Based Quantification of the Systemic Interplay between Glucose and Fatty Acids in the Postprandial State.
PloS one 20150910 9
In metabolic diseases such as Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease, the systemic regulation of postprandial metabolite concentrations is disturbed. To understand this dysregulation, a quantitative and temporal understanding of systemic postprandial metabolite handling is needed. Of particular interest is the intertwined regulation of glucose and non-esterified fatty acids (NEFA), due to the association between disturbed NEFA metabolism and insulin resistance. However, postprandi ...[more]
