Ontology highlight
ABSTRACT:
SUBMITTER: Roth-Alpermann C
PROVIDER: S-EPMC1544170 | biostudies-other | 2006 Jul
REPOSITORIES: biostudies-other
Proceedings of the National Academy of Sciences of the United States of America 20060707 29
Homeostasis is a key concept in biology. It enables ecosystems, organisms, organs, and cells to adjust their operating range to values that ensure optimal performance. Homeostatic regulation of the strength of neuronal connections has been shown to play an important role in the development of the nervous system. Here we investigate whether mature neurons also possess mechanisms to prevent the strengthening of input synapses once the limit of their operating range has been reached. Using electrop ...[more]