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The human microbiome: at the interface of health and disease.

ABSTRACT: Interest in the role of the microbiome in human health has burgeoned over the past decade with the advent of new technologies for interrogating complex microbial communities. The large-scale dynamics of the microbiome can be described by many of the tools and observations used in the study of population ecology. Deciphering the metagenome and its aggregate genetic information can also be used to understand the functional properties of the microbial community. Both the microbiome and metagenome probably have important functions in health and disease; their exploration is a frontier in human genetics.

SUBMITTER: Cho I 

PROVIDER: S-EPMC3418802 | biostudies-other | 2012 Mar

REPOSITORIES: biostudies-other

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The human microbiome: at the interface of health and disease.

Cho Ilseung I   Blaser Martin J MJ  

Nature reviews. Genetics 20120313 4

Interest in the role of the microbiome in human health has burgeoned over the past decade with the advent of new technologies for interrogating complex microbial communities. The large-scale dynamics of the microbiome can be described by many of the tools and observations used in the study of population ecology. Deciphering the metagenome and its aggregate genetic information can also be used to understand the functional properties of the microbial community. Both the microbiome and metagenome p  ...[more]

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