Ontology highlight
ABSTRACT:
SUBMITTER: Pickard D
PROVIDER: S-EPMC3592008 | biostudies-other | 2013 Mar
REPOSITORIES: biostudies-other
Journal of bacteriology 20130111 6
A transposon-based, genomewide mutagenesis screen exploiting the killing activity of a lytic ViII bacteriophage was used to identify Salmonella enterica serovar Typhi genes that contribute to Vi polysaccharide capsule expression. Genes enriched in the screen included those within the viaB locus (tviABCDE and vexABCDE) as well as oxyR, barA/sirA, and yrfF, which have not previously been associated with Vi expression. The role of these genes in Vi expression was confirmed by constructing defined n ...[more]