Ontology highlight
ABSTRACT:
SUBMITTER: Waaijers S
PROVIDER: S-EPMC3813849 | biostudies-other | 2013 Nov
REPOSITORIES: biostudies-other
Genetics 20130826 3
The generation of genetic mutants in Caenorhabditis elegans has long relied on the selection of mutations in large-scale screens. Directed mutagenesis of specific loci in the genome would greatly speed up analysis of gene function. Here, we adapt the CRISPR/Cas9 system to generate mutations at specific sites in the C. elegans genome. ...[more]