Ontology highlight
ABSTRACT:
SUBMITTER: Wu JW
PROVIDER: S-EPMC4829845 | biostudies-other | 2016 Apr
REPOSITORIES: biostudies-other
Scientific reports 20160413
Clonal heterogeneity and selection underpin many biological processes including development and tumor progression. Combinatorial fluorescent protein expression in germline cells has proven its utility for tracking the formation and regeneration of different organ systems. Such cell populations encoded by combinatorial fluorescent proteins are also attractive tools for understanding clonal expansion and clonal competition in cancer. However, the assignment of clonal identity requires an analytica ...[more]