ChAMP: updated methylation analysis pipeline for Illumina BeadChips.

ABSTRACT: The Illumina Infinium HumanMethylationEPIC BeadChip is the new platform for high-throughput DNA methylation analysis, effectively doubling the coverage compared to the older 450?K array. Here we present a significantly updated and improved version of the Bioconductor package ChAMP, which can be used to analyze EPIC and 450k data. Many enhanced functionalities have been added, including correction for cell-type heterogeneity, network analysis and a series of interactive graphical user interfaces.ChAMP is a BioC package available from https://bioconductor.org/packages/release/bioc/html/[e-mail] or [e-mail] or [e-mail] data are available at Bioinformatics online.

SUBMITTER: Tian Y 

PROVIDER: S-EPMC5860089 | biostudies-other | 2017 Dec

REPOSITORIES: biostudies-other