Dataset Information
New pregnane glycosides from Gymnema sylvestre.
Ontology highlight
ABSTRACT:
SUBMITTER: Xu R
PROVIDER: S-EPMC6272391 | biostudies-other | 2015
REPOSITORIES: biostudies-other
Publications
New pregnane glycosides from Gymnema sylvestre.
Molecules (Basel, Switzerland) 20150212 2
Four new pregnane glycosides 1-4 were isolated from the ethanol extract of the stem of Gymnema sylvestre and named gymsylvestrosides A-D. Hydrolysis of compound 1 under the catalysis of Aspergilus niger β-glucosidase afforded compound 5 (gymsylvestroside E). Their structures were determined by spectroscopic methods such as HRESIMS, 1D and 2D NMR, as well as HMQC-TOCSY experiment. Compounds 1-4 were screened for Saccharomyces cerevisiae α-glucosidase inhibitory activity. ...[more]