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FusionSeq: Finding Fusions with Paired-End RNA-Seq

ABSTRACT:

We have developed FusionSeq to identify fusion transcripts from paired-end RNA-sequencing. FusionSeq includes filters to remove spurious candidate fusions with artifacts such as misalignments or random pairing of transcript fragments and it ranks candidates according to several statistics. It also has a module to identify exact sequences at breakpoint junctions. FusionSeq detected known and novel fusions in a specially sequenced calibration data set, including 8 cancers with and without known rearrangements.

PROVIDER: phs000311 | dbGaP |

SECONDARY ACCESSION(S): PRJNA74883PRJNA74881

REPOSITORIES: dbGaP

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