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Mathematical modelling of the sporulation-initiation network in Bacillus subtilis.

ABSTRACT: Mathematical modelling of the sporulation-initiation network in Bacillus subtilis.

SUBMITTER: Sara Jabbari

PROVIDER: 33 | FAIRDOMHub | 2014-07-16

REPOSITORIES: FAIRDOMHub

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Mathematical modelling of the sporulation-initiation network in Bacillus subtilis revealing the dual role of the putative quorum-sensing signal molecule PhrA.

Jabbari Sara S Heap John T JT King John R JR

Bulletin of mathematical biology 20100318 1

Bacillus subtilis cells may opt to forgo normal cell division and instead form spores if subjected to certain environmental stimuli, for example nutrient deficiency or extreme temperature. The resulting spores are extremely resilient and can survive for extensive periods of time, importantly under particularly harsh conditions such as those mentioned above. The sporulation process is highly time and energy consuming and essentially irreversible. The bacteria must therefore ensure that this route ...[more]

PMID: 20238180

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