Dataset Information


Transcriptomic analysis of Aspergillus flavus and its ASPES transcription factor deletion strains

ABSTRACT: RNA-seq was used to compare differential gene expressions for Aspergillus flavus wild type strain and ASPES transcription factor deletion strains.The goals of this study are to explore the aflatoxin regulation pathway in A. flavus. Overall design: Examination of differential gene expressions by RNA-seq in Aspergillus flavus wild type strain under both YES and YEP, and two APSES transcription factor mutant strains(AfRafA knoutout strain and AfStuA)

INSTRUMENT(S): Illumina HiSeq 2000 (Aspergillus flavus)

ORGANISM(S): Aspergillus Flavus

SUBMITTER: Guangshan Yao  

PROVIDER: GSE107025 | GEO | 2018-12-25


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Exploration of the Regulatory Mechanism of Secondary Metabolism by Comparative Transcriptomics in Aspergillus flavus.

Yao Guangshan G   Yue Yuewei Y   Fu Yishi Y   Fang Zhou Z   Xu Zhangling Z   Ma Genli G   Wang Shihua S  

Frontiers in microbiology 20180807

Mycotoxins cause a huge threaten to agriculture, food safety, and human and animal life. Among them, aflatoxins (AFs) have always been considered the most potent carcinogens, and filamentous fungi from Aspergillus genus are their major producers, especially A. flavus. Although the biosynthesis path of these chemicals had been well-identified, the regulatory mechanisms controlling expression of AF gene cluster were poorly understood. In this report, genome-wide transcriptome profiles of A. flavus  ...[more]

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